Tottenham’s top scorer Harry Kane misses out because of his latest ankle injury, so Son Heung-min or Fernando Llorente will play up front.
Deli Alli is doubtful with a fractured hand, while Serge Aurier, Eric Dier and Erik Lamela are all still out.
Huddersfield head coach Jan Siewert has intimated that he will again rotate his squad as he plans for next season.
Isaac Mbenza is a doubt due to illness but Demeaco Duhaney and Laurent Depoitre are nearing full fitness.
- Harry Kane vows to “come back stronger” – but will Spurs miss him?
- VAR will lead to more penalties – Vertonghen
MOTD COMMENTATOR’S NOTES
@SteveBowercomm: Well, if they weren’t favourites in their titanic Champions League battle with Manchester City in midweek, then all the expectations are on Spurs to make it back-to-back Premier League victories in their spectacular new home.
Complacency is likely to be their biggest challenge, even without the injured Harry Kane. They are fully aware there is little margin for error in the chase for Champions League football, having lost four of their last six league matches, especially against the relegated bottom club.
Huddersfield players are fighting for their own immediate futures in their remaining matches and will hope to be inspired rather than overawed at the Tottenham Hotspur Stadium.
VIEW FROM THE DUGOUT
Tottenham manager Mauricio Pochettino: “The massive risk is how we are going to approach the game. We have a lot of players who played 90 minutes [in midweek] who are not in a condition to play.
“We have a strong squad; rather than rest players we want to provide the team with good energy and fresh legs to be sure we can approach the game in the best condition and be sure we are going to get the three points.”
Huddersfield Town head coach Jan Siewert: “When you look at our opponents, of course it is not easy but we have to try.
“No one expects anything from us. Everyone expects something from them. So we are free to go there and give our best.
“We try to build some momentum for next season; this is our ambition.”
Tottenham have got a lot of work to do to secure a top-four place and this is a situation where they should pick their best team, get the game won – and then they can take their foot off the pedal.
- Tottenham are unbeaten in seven top-flight matches against Huddersfield since a 2-1 home defeat in April 1956 (W4, D3).
- Huddersfield have lost all three Premier League meetings by an aggregate score of 8-0.
- Spurs could win their first four Premier League games against a particular opponent without conceding for just the second time, having also done it versus Cardiff.
- Tottenham have lost four of their past six league fixtures, ending a five-match winless streak by beating Crystal Palace last time out.
- They have won both matches played at the Tottenham Hotspur Stadium in all competitions and are yet to concede a goal at their new home.
- Spurs have lost four of their eight league matches following Champions League fixtures this campaign.
- They have won 14 and lost just two of their 16 league games against the sides currently in the bottom half of the table.
- Tottenham have scored 12 of their last 14 Premier League goals in the second half of games.
- They have conceded 14 of their 34 league goals, or 41%, in the last 15 minutes of their matches.
- Huddersfield have lost 18 of their last 20 league matches, winning once and failing to score in 11 of those fixtures.
- The Terriers have been beaten in nine of their past 10 away league encounters, drawing the other.
- They have lost all nine league encounters against the established top-six clubs this season, conceding 26 goals.
- Huddersfield could become the first club to concede a penalty in four straight top-flight fixtures since Stoke in January 2014.
- Goalkeeper Ben Hamer has conceded 17 goals in just six league matches this season, conceding a goal every 27 minutes on average.